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Nursing Pharmacology Essentials: Memorize 79 Flashcards on LADME, Receptors and Therapeutic Index

Study nursing pharmacology vocabulary with 79 flashcards: LADME, half-life, agonists vs antagonists, EC50, therapeutic index, atropine and drug interactions.

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Every nursing pharmacology exam starts the same way: before any drug class, you are expected to know the vocabulary that describes what drugs do and what the body does to them. The Nursing Pharmacology Essentials deck on Flip It (deck code TX6245, 79 cards) is exactly that vocabulary layer: pharmacokinetics, pharmacodynamics, receptor theory, safety terminology and regulation, written as short term-to-definition cards. This guide shows what is inside and the most efficient order to learn it.

Study this deck: Nursing Pharmacology Essentials

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Question

Pharmacology

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Tap the card for the answer · swipe right if you knew it, left if not

Ten cards from the deck

FrontBack
What does LADME stand for in pharmacokinetics?Liberation, Absorption, Distribution, Metabolism, and Excretion
Half-life (t½) of a drugThe time required for the drug's plasma concentration to reduce by half
First-pass effectThe initial metabolism of an orally administered drug in the liver before it reaches systemic circulation
Partial agonistA drug that binds to a receptor and produces a biological response lower than that of a full agonist
EC50The drug concentration that produces 50% of the maximum efficacy, used to compare drug potencies
Therapeutic indexThe ratio of the dose that produces toxicity to the dose that produces the desired therapeutic effect
What drugs commonly have a narrow therapeutic index?Warfarin, some antiepileptics, aminoglycoside antibiotics, and most anti-cancer drugs
AtropineAn anticholinergic drug used to treat bradycardia and as an antidote for certain poisonings
PolypharmacyThe concurrent use of multiple medications by a patient, which can increase the risk of drug interactions
Parenteral administrationDrug delivery by routes other than the gastrointestinal tract (intravenous, intramuscular, subcutaneous)

The four blocks of the deck

  1. Pharmacokinetics (what the body does to the drug): LADME, liberation, absorption, distribution, metabolism, excretion, half-life, volume of distribution (VD), clearance, bioavailability, first-pass effect, lipophilicity, blood-brain barrier, enteral vs parenteral routes.
  2. Pharmacodynamics (what the drug does to the body): receptor, agonist, antagonist, partial agonist, efficacy, potency, EC50, binding affinity, dose-response relationship, G protein-coupled receptors, ligand-gated ion channels, enzyme inhibitor, drug tolerance.
  3. Safety and the nursing perspective: therapeutic index, narrow therapeutic index, therapeutic window, therapeutic drug monitoring, adverse drug reaction, side effect vs adverse effect, contraindication, drug-drug interaction, synergistic vs antagonistic interactions, polypharmacy, pharmacovigilance, placebo effect, toxicology.
  4. Drugs, transmitters and the system: morphine and opioid agonists, atropine, anticholinergic vs cholinergic drugs, acetylcholine, dopamine, serotonin, GABA; drug discovery, lead compound, drug development, the FDA's two approval requirements, generic vs brand-name, prescription vs over-the-counter, pharmacogenomics, pharmacogenetics, personalized medicine, posology, pharmacotherapy.

Study tips that fit this deck

Sort every card into "kinetics" or "dynamics" before you answer. The deck's second card gives you the rule (kinetics = what the body does to the drug, dynamics = what the drug does to the body). If you name the side first, half of the definition writes itself: half-life, clearance and bioavailability are all body-side measurements; agonist, EC50 and affinity are all drug-side.

Learn the safety terms as a nested set. Therapeutic window sits between the minimum effective and minimum toxic concentrations; therapeutic index is the ratio of those two doses; a narrow index is what triggers therapeutic drug monitoring; and the deck names the drugs that need it (warfarin, aminoglycosides, antiepileptics, anticancer agents). Reviewing those five cards in a row turns them into one story rather than five definitions.

Working through it

Do the 79 cards in two sessions split along the kinetics/dynamics line, then let spaced repetition handle the rest. Expect the numeric and ratio terms (EC50, therapeutic index, volume of distribution) to come back most often; the neurotransmitter cards will be gone after two reviews.

Log in at flip-it.app, find Nursing Pharmacology Essentials or the code TX6245 in the library, and start with block one.

Keep going

Once the vocabulary is solid, the deeper deck covered in Pharmacology Fundamentals: 99 flashcards on pharmacokinetics, receptors and drug classes moves into actual drug classes.

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